性 别：男
出生年月：1979年9月
职 称：副教授 硕导
所 在 系： 生物制药
办 公 室： 6-419
电 话：0571-86843193
电子邮件：heyl79@zstu.edu.cn
主要学习与工作经历
1. 1999.09-2003.06 内蒙古民族大学 本科；
2. 2003.09-2006.06 西北农林科技大学 硕士；
3. 2006.09-2011.06 西北农林科技大学 博士；
4. 2008.12-2010.09美国UT Health Science Center at San Antonio(UTHSCSA) 访问学者；
5. 2011.07-2016.02 宁夏大学 生命科学公司/西部特色生物资源保护与利用教育部重点实验室 教学科研；
6. 2016.03-至今 B-Sports 生命科学与医药公司 教学科研。
主要研究方向
1. 动物疫病新型疫苗开发;
2. 病原微生物与宿主免疫研究。
获奖与荣誉
2012年度获宁夏自治区“全职引进优秀博士”称号；
2020年度浙江省高校产学研联盟“博士入企”考核优秀；
2023年度获B-Sports“三育人”先进个人称号；
2023年度B-Sports“校科技贡献奖”；
2023年度第十五届中国商业联合会服务业科技创新一等奖（4/6）；
2025年度B-Sports“校先进工作者”。
主要学术及社会兼职
浙江省畜牧兽医学会理事、浙江省免疫学会动物免疫专业委员会委员、浙江省农业农村厅人畜共患病防控专家；
中国细胞生物学学会会员、中国生物化学与分子生物学会会员、中国农业生物技术学会动物生物技术分会会员、浙江省农学会会员。
科研教学项目
1、主持及主持结题科研项目
主持或主持结题国家自然科学基金项目1项、留学回国人员创新创业项目1项、省（自治区）自然科学基金项目1项、省公益技术应用研究项目2项、省“领雁”研发攻关计划项目子课题1项、新疆建设兵团科技计划项目子课题1项、省 “三农九方”农业科技协作计划项目子课题2项、省高校生物学重中之重（一级）学科带头人培养专项1项、企业委托重大横向课题1项（合同金额600万元）和其他横向项目8项。
2、参与科研项目
作为科研骨干参于国家“973”计划子课题、“973”前期研究专项和浙江省重点研发或“尖兵”“领雁”科技计划项目5项、以第二或第三参与人参与国家自然科学基金5项等。
3、教学改革项目
主持结题校级《免疫学》优质课程建设项目1项、校级《生物制药工艺学》课程思政示范建设项目1项；以第二申请人申请获批《基因工程技术制备门冬酰胺酶(冻干粉针)工艺》国家级虚拟仿真实验教学项目1项。
学术论文（第一作者和通讯作者）
1. Linyi Dai, Lei Yang, Vitalii Nedosekov, Jing Ma, Weihuan Fang, Huapeng Feng, Jianhong Shu, Yulong He*. Advancements in Nanomaterial-Based Adjuvants for Animal Vaccines. Materials Today Bio. 2026, 38(4):103123. (SCI, IF=10.2 医学一区TOP)
2. Yuanxiu Li, Wenqing Chai, Hang Pan, Weihuan Fang, Huapeng Feng, Jianhong Shu, Yulong He*. Genomic characterization of Actinobacillus pleuropneumoniae serovars 5, 8, and 15 strains from diseased pigs in eastern Chinese provinces. Virulence. 2026, 17(1):2620200. (SCI, IF=5.4 农林科学一区TOP)
3. Yanling Zhuo, Guiying Wu, Yuanyi Yang, Shuang Li, Yan Wang, Xinyu Huang, Wanping Wu, Qizhuang Lv*, Yulong He* and Lei Yang*. Pollen-inspired multifunctional nanocarrier for porcine circovirus 2 vaccine delivery. Journal of Nanobiotechnology. 2026, 24:526. (SCI, IF=12.6 生物学一区TOP)
4. Yulong He, Yuehong Wu, Anuja Mishra, Victor Acha, Thomas Andrews, Peter J. Hornsby*. Biosensor technology in aging research and age-related diseases. Ageing Research Reviews. 2012,11(1):1-9(SCI, 5年IF=14.9医学一区TOP)
5. Yu Duan, Yue Hao, Huapeng Feng, Jianhong Shu* and Yulong He*. Research progress on Haemophilus parasuis vaccines. Front. Vet. Sci. 2025, 12:1492144. (SCI, 高被引论文)
6. Lixin Li, Xiaxia Tong, Jianhong Shu, Huapeng Feng, Yanping Quan* and Yulong He*. Efficacy Evaluation of a VR-2332-Based Modified Live Vaccine Against NADC30-like PRRSV in China. Vaccines. 2025, 13: 538. (SCI)
7. Jinqi Shu, Gaojian Li, Jianhong Shu, Huapeng Feng, Yulong He*. CD40 Ligand Potentiates Immunogenecity of Mycoplasma pneumoniae Subunit Vaccine Candidate in a Murine Model. Current Issues in Molecular Biology. 2025, 47(1): 37. (SCI)
8. Bin Jiang, Ying Zhang, Gaojian Li, Yanping Quan, Jianhong Shu, Huapeng Feng, Yulong He*. Research progress on immune evasion of Mycoplasma hyopneumoniae. Microorganisms. 2024, 12(7): 1439. (SCI)
9. Gaojian Li, Jinqi Shu, Jing Jin, Jianhong Shu, Huapeng Feng, Jian Chen and Yulong He*. Development of a Multi-Epitope Vaccine for Mycoplasma hyopneumoniae and Evaluation of Its Immune Responses in Mice and Piglets. International Journal of Molecular Sciences. 2022, 23(14):7899. (SCI)
10. Yu Tao, Rui Yang, Jianhong Shu, Wenqian Zheng, Jian Chen, Yuehong Wu and Yulong He*. Immune responses induced by a combined vaccination with a recombinant chimera of Mycoplasma hyopneumoniae antigens and capsid virus-like particles of porcine circovirus type 2, BMC Veterinary Research, 2020, 16(1):342.(SCI)
11. Gaojian Li, Enoch Obeng, Jinqi Shu, Jianhong Shu, Jian Chen, Yuehong Wu* and Yulong He*. Genomic variability and post-translational protein processing enhance the immune evasion of Mycoplasma hyopneumoniae and its interaction with the porcine immune system. Frontiers in Immunology. 2020, 7(11): 510943. (SCI)
12. Yu Tao, Gaojian Li, Wenqian Zheng, Jianhong Shu, Jian Chen, Fang Yang, Yuehong Wu*, and Yulong He*. Development of a Combined Genetic Engineering Vaccine for Porcine Circovirus Type 2 and Mycoplasma Hyopneumoniae by a Baculovirus Expression System. International Journal of Molecular Sciences. 2019, 20, 4425. (SCI)
13. Rui Yang, Yu Tao, Gaojian Li, Jian Chen, Jianhong Shu* and Yulong He*. Immunoenhancement of recombinant Neisseria meningitides PorB protein on porcine circovirus type 2 and Mycoplasma hyopneumoniae genetically engineered vaccines. Protein & Peptide Letters, 2019, 26(10): 776 - 784. (SCI)
14. Yu Tao, Jianhong Shu, Jian Chen, Yuehong Wu*, Yulong He*. A concise review of vaccines against Mycoplasma hyopneumoniae. Research in Veterinary Science, 2019,123:144-152. (SCI)
15. Yi Yang, Xiaokang Liu, Ting Wu, Wenping Zhang, Jianhong Shu*, Yulong He*, ShaoJun Tang. Quercetin attenuates AZT-induced neuroinflammation in the CNS. Scientific Reports, 2018, 8(1):6194. (SCI)
16. Minxia Ke, Quan He, Danping Hong, Ouyang Li, Mengyi Zhu, Wen‑Bin Ou, Yulong He*, Yuehong Wu*. Leukemia inhibitory factor regulates marmoset induced pluripotent stem cell proliferation via a PI3K/Akt‑dependent Tbx‑3 activation pathway. International Journal of Molecular Medicine, 2018, 42(1):131-140. (SCI)
17. Danping Hong, Jiongyan Ding, Ouyang Li, Quan He, Minxia Ke, Mengyi Zhu, Lili Liu, Wen-Bin Ou, Yulong He* and Yuehong Wu*. Human-induced pluripotent stem cell-derived macrophages and their immunological function in response to tuberculosis infection. Stem Cell Research & Therapy, 2018, 9(1):49. (SCI)
18. Yuehong Wu, Jianhong Shu, Chengwen He, Min Li, Yujiong Wang, Wenbin Ou, Yulong He*. ROCK inhibitor Y27632 promotes proliferation and diminishes apoptosis of marmoset iPS cells by suppressing expression and activity of Caspase-3. Theriogenology. 2016, 85(2):302-314. (SCI)
19. Yulong He, Yuehong Wu, Fusheng Quan, Yonggang Liu, Yong Zhang*. Comparative analysis of sequence of myostatin gene and promoter in Qinchuan and Red Angus cattle. Genetics and Molecular Research. 2013,12(3):3398-3406. (SCI)
20. Yulong He, Yuehong Wu, Zhigang Lan, Yonggang Liu, Yong Zhang*. Molecular analysis of the first intron in the bovine myostatin gene, Molecular biology reports. 2011,38(7):4643-9. (SCI)
21. Yulong He, Yuehong Wu, Xiaoning He, Fengjun Liu, Xiaoying He, Yong Zhang*. An immortalized goat mammary epithelial cell line induced with human telomerase reverse transcriptase (hTERT) gene transfer, Theriogenology. 2009,71(9):1417-24.（SCI）
发明专利(第一发明人申请发明专利19件，授权5件，实施转化3项)
1. 何玉龙, 陶宇, 舒建洪, 陈健, 吴月红, 杨芳. 猪支原体肺炎和猪圆环病毒2型重组蛋白及制备二联疫苗. 专利号：ZL201811179696.3.
2. 何玉龙, 陶宇, 舒建洪, 陈健, 杨芳, 童夏霞, 盛敏成. 猪支原体肺炎和猪圆环病毒二联基因工程疫苗制备方法. 专利号：ZL201910200702.7.
3. 何玉龙, 李高建, 舒建洪, 舒金琪, 查银河. 一种基于反向疫苗学技术的猪肺炎支原体多表位基因工程亚单位疫苗的制备方法及其应用. ZL202111664581.5.
4. 何玉龙, 宋育聪, 李香平, 查银河, 舒建洪, 王英博, 冯华朋, 潘颂佳. 一种基于鸽腺病毒Hexon蛋白的诊断试剂盒及应用. 专利号：ZL202411461485.4.
5. 何玉龙, 查银河, 王英博, 潘颂佳, 舒建洪, 冯华朋, 童夏霞. 一种猪圆环病毒3型抗原检测试剂条及制备方法和应用. 专利号：ZL202411090226.5.
参编教材情况
参编高等教育出版社《免疫学原理与技术》（第一版）、（第二版）新形态教材和《新药药理学》数字课程各1项。
